The BETRNet focus of Project 1 is thus to create a genetically engineered mouse model based on VSIG10L to understand the transformation from squamous epithelium to metaplastic Barrett’s epithelium. The significance of Project 1 is clearly in first building on our successful discovery of the first familial susceptibility genetic variant by understanding how this gene functions in metaplastic

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Betrnet Stem Cells and the Origins of Barrett's Esophagus Project 3 RF Ablation (BetrnetRF) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.

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The Barrett's Esophagus Translational Research Network (BETRNet) was established in 2011 through funding from the National Cancer Institute.

26/09/2019 BETRNet, a multi-disciplinary, multi-institutional collaboration co-sponsored by NCI's Division of Cancer Prevention and Division of Cancer Biology, was established to centralize and enhance efforts to understand Barrett's esophagus (BE) and to prevent esophageal adenocarcinoma (EA).. BE is the only known pre-cursor lesion to EA, a cancer with the fastest growing incidence rate in the United